Comparative Analysis of Umbilical Nodules in Male and Female Patients: A 20-Year Retrospective Study / Análisis comparativo de los nódulos umbilicales en pacientes masculinos y femeninos: un estudio retrospectivo de 20 años

Background and aims The umbilicus is known to receive metastatic malignancy from diverse visceral organs. Accurate and correct diagnosis of umbilical lesions is imperative since metastatic malignancy signifies a serious underlying situation with dire prognosis. Identification of demographic features that can contribute to diagnostic resolution of umbilical lesions is desirable. We analyzed umbilical biopsies received over a 20-year period to determine any gender distinctive attributes of umbilical nodules. Materials and method All umbilical biopsies received in our department from 1st January 2000 to 31st December 2019 were identified and analyzed. Data acquired included patient's gender, age, date of biopsy, type of biopsy and histopathological diagnoses and these were analyzed using computer software. Results There were 67 umbilical biopsies from 22 males and 45 females giving a male: female ratio of 1:2. The difference between the mean age (SD) of male patients [47.8 years (19.4 years)] and that of the females [42.8 years (13.9 years)] was not statistically significant (p=0.28). Twenty-five of the 67 umbilical lesions were benign while 42 were malignant. About 90.9% of biopsies in males were malignant and 9.1% benign while 48.9% of biopsies in females were malignant and 51.1% benign. The odds of malignant umbilical biopsy in males compared to females is 10.5 [OR=10.5; 95% CI=2.2–50.1)]. Conclusion Umbilical biopsies were relatively infrequent in our practice and were more common in females than males. Umbilical lesions presented by males are mostly malignant. Overall, 78% of all umbilical lesions in females were of gynecological derivation (AU)

Antecedentes y objetivo Se sabe que en el ombligo se presentan metástasis de neoplasias de diversos órganos viscerales. Es imperativo el diagnóstico preciso y correcto de las lesiones umbilicales, ya que la caracterización metastásica implica una situación subyacente grave con un pronóstico nefasto. Es deseable la identificación de las características demográficas que pueden contribuir a la resolución diagnóstica de las lesiones umbilicales. Analizamos las biopsias umbilicales recibidas durante un período de 20 años para determinar los atributos distintivos de género de los nódulos umbilicales. Material y método Se identificaron y analizaron todas las biopsias umbilicales recibidas en nuestro departamento desde el 1 de enero de 2000 hasta el 31 de diciembre de 2019. Los datos adquiridos incluyeron el sexo del paciente, la edad, la fecha de la biopsia, el tipo de biopsia y los diagnósticos histopatológicos y se analizaron mediante un software informático. Resultados Hubo 67 biopsias umbilicales de 22 hombres y 45 mujeres dando una relación hombre: mujer de 1:2. La diferencia entre la edad media (DE) de los hombres [47,8 años (19,4 años)] y la de las mujeres [42,8 años (13,9 años)] no fue estadísticamente significativa (P=0,28). Veinticinco de las 67 lesiones umbilicales fueron benignas mientras que 42 fueron malignas. El 90,9% de las biopsias en hombres fueron malignas y el 9,1% benignas, mientras que el 48,9% de las biopsias en mujeres fueron malignas y el 51,1% benignas. El riesgo de que una biopsia umbilical fuera maligna en hombres en comparación con mujeres fue de 10,5 [RP=10,5; IC del 95%=2,2 a 50,1)]. Conclusión Las biopsias umbilicales fueron relativamente poco frecuentes en nuestra práctica y fueron más comunes en mujeres que en hombres. Las lesiones umbilicales que presentan los varones son en su mayoría malignas. En general, el 78% de todas las lesiones umbilicales en mujeres fueron de derivación ginecológica (AU)

[Artículo traducido] Análisis comparativo de los nódulos umbilicales en pacientes masculinos y femeninos: un estudio retrospectivo de 20 años / Comparative Analysis of Umbilical Nodules in Male and Female Patients: A 20-Year Retrospective Study

Antecedentes y objetivo Se sabe que en el ombligo se presentan metástasis de neoplasias de diversos órganos viscerales. Es imperativo el diagnóstico preciso y correcto de las lesiones umbilicales, ya que la caracterización metastásica implica una situación subyacente grave con un pronóstico nefasto. Es deseable la identificación de las características demográficas que pueden contribuir a la resolución diagnóstica de las lesiones umbilicales. Analizamos las biopsias umbilicales recibidas durante un periodo de 20 años para determinar los atributos distintivos de género de los nódulos umbilicales. Material y método Se identificaron y analizaron todas las biopsias umbilicales recibidas en nuestro departamento desde el 1 de enero del 2000 hasta el 31 de diciembre del 2019. Los datos adquiridos incluyeron el sexo del paciente, la edad, la fecha de la biopsia, el tipo de biopsia y los diagnósticos histopatológicos, y se analizaron mediante un software informático. Resultados Hubo 67 biopsias umbilicales de 22 hombres y 45 mujeres dando una relación hombre: mujer de 1:2. La diferencia entre la edad media (DE) de los hombres (47,8 años [19,4 años]) y la de las mujeres (42,8 años [13,9 años]) no fue estadísticamente significativa (p=0,28). Veinticinco de las 67 lesiones umbilicales fueron benignas, mientras que 42 fueron malignas. El 90,9% de las biopsias en hombres fueron malignas y el 9,1% benignas, mientras que el 48,9% de las biopsias en mujeres fueron malignas y el 51,1%, benignas. El riesgo de que una biopsia umbilical fuera maligna en hombres en comparación con mujeres fue de 10,5 (RP=10,5; IC del 95%=2,2 a 50,1). Conclusión Las biopsias umbilicales fueron relativamente poco frecuentes en nuestra práctica y fueron más comunes en mujeres que en hombres. Las lesiones umbilicales que presentan los varones son en su mayoría malignas. En general, el 78% de todas las lesiones umbilicales en mujeres fueron de derivación ginecológica (AU)

Background and aims The umbilicus is known to receive metastatic malignancy from diverse visceral organs. Accurate and correct diagnosis of umbilical lesions is imperative since metastatic malignancy signifies a serious underlying situation with dire prognosis. Identification of demographic features that can contribute to diagnostic resolution of umbilical lesions is desirable. We analyzed umbilical biopsies received over a 20-year period to determine any gender distinctive attributes of umbilical nodules. Materials and method All umbilical biopsies received in our department from 1st January 2000 to 31st December 2019 were identified and analyzed. Data acquired included patient's gender, age, date of biopsy, type of biopsy and histopathological diagnoses and these were analyzed using computer software. Results There were 67 umbilical biopsies from 22 males and 45 females giving a male: female ratio of 1:2. The difference between the mean age (SD) of male patients [47.8 years (19.4 years)] and that of the females [42.8 years (13.9 years)] was not statistically significant (P=0.28). Twenty-five of the 67 umbilical lesions were benign while 42 were malignant. About 90.9% of biopsies in males were malignant and 9.1% benign while 48.9% of biopsies in females were malignant and 51.1% benign. The odds of malignant umbilical biopsy in males compared to females is 10.5 [OR=10.5; 95% CI=2.2–50.1)]. Conclusion Umbilical biopsies were relatively infrequent in our practice and were more common in females than males. Umbilical lesions presented by males are mostly malignant. Overall, 78% of all umbilical lesions in females were of gynecological derivation (AU)

Comparative Analysis of Umbilical Nodules in Male and Female Patients: A 20-Year Retrospective Study.

BACKGROUND AND AIMS: The umbilicus is known to receive metastatic malignancy from diverse visceral organs. Accurate and correct diagnosis of umbilical lesions is imperative since metastatic malignancy signifies a serious underlying situation with dire prognosis. Identification of demographic features that can contribute to diagnostic resolution of umbilical lesions is desirable. We analyzed umbilical biopsies received over a 20-year period to determine any gender distinctive attributes of umbilical nodules. MATERIALS AND METHOD: All umbilical biopsies received in our department from 1st January 2000 to 31st December 2019 were identified and analyzed. Data acquired included patient's gender, age, date of biopsy, type of biopsy and histopathological diagnoses and these were analyzed using computer software. RESULTS: There were 67 umbilical biopsies from 22 males and 45 females giving a male: female ratio of 1:2. The difference between the mean age (SD) of male patients [47.8 years (19.4 years)] and that of the females [42.8 years (13.9 years)] was not statistically significant (p=0.28). Twenty-five of the 67 umbilical lesions were benign while 42 were malignant. About 90.9% of biopsies in males were malignant and 9.1% benign while 48.9% of biopsies in females were malignant and 51.1% benign. The odds of malignant umbilical biopsy in males compared to females is 10.5 [OR=10.5; 95% CI=2.2-50.1)]. CONCLUSION: Umbilical biopsies were relatively infrequent in our practice and were more common in females than males. Umbilical lesions presented by males are mostly malignant. Overall, 78% of all umbilical lesions in females were of gynecological derivation.